In many states, minors can get abortions, treatment for sexually transmitted diseases, or mental health services without their parents' knowledge or consent. In the era of electronic health information exchange (HIE), however, maintaining this confidentiality is a vexing challenge. Information about minors is subject to myriad laws that require healthcare providers to treat it differently than health information about adults. This issue brief provides an overview of the laws governing disclosure of minors' health information and spotlights the challenges that these laws pose to comprehensive electronic HIE.